Ferric chloride for hemostasis of malignant neoplastic wounds: a scoping review
DOI:
https://doi.org/10.5327/Z1414-44251070%20Keywords:
Ferric chloride, Hemostasis, Wounds and injuries, Oncology nursingAbstract
Objective: To map the scientific evidence on the use of ferric chloride for hemostasis of bleeding malignant neoplastic wounds in adult patients within the healthcare context. Method: A scoping review conducted following the recommendations of the JBI. The electronic databases Medical Literature Analysis and Retrieval System Online (MEDLINE)/PubMed, Embase, Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), EBSCO, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), and gray literature sources were searched from inception to August 15, 2025. Results: A total of 31,952 records were identified, of which 17 were included. The studies addressed the use of ferric chloride in different formulations and concentrations across gynecology/obstetrics, dentistry, and dermatology, among surgical patients. No serious adverse events were reported following its use, and no study included patients with bleeding malignant neoplastic wounds. Conclusion: Ferric chloride has been used as a hemostatic agent in adults with various health conditions. However, the absence of specific evidence in bleeding neoplastic wounds highlights the need for further studies to investigate its effectiveness and safety in this patient population.
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